Geometric modelling of the human cornea: A new approach for the study of corneal ectatic disease. A pilot investigation

Abstract

The aim of this study was to describe the application of a new bioengineering graphical technique based on geometric custom modelling capable to detect and to discriminate small variations in the morphology of the corneal surface. A virtual 3D solid custom model of the cornea was obtained employing Computer Aided Geometric Design tools, using raw data from a discrete and finite set of spatial points representative of both sides of the corneal surface provided by a corneal topographer. Geometric reconstruction was performed using B-Spline functions, defining and calculating the representative geometric variables of the corneal morphology of patients under clinical diagnosis of keratoconus.