Sweetener influences plasma concentration of flavonoids in humans after an acute intake of a new (poly)phenol-rich beverage
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This work was funded by the Spanish MINECO through Research Project AGL2016-75332-C2-1-R (AEI/FEDER, UE). V.A. was supported by FPI (BES-2017-079754) grant of the Fellowship Program from the Spanish Ministry of Science, Innovation, and Universities (MICIU).Publication date
2020Publisher
ElsevierBibliographic Citation
Agulló, Vicente & Domínguez-Perles, Raúl & Cristina, Garcia-Viguera. (2020). Sweetener influences plasma concentration of flavonoids in humans after an acute intake of a new (poly)phenol-rich beverage. Nutrition, Metabolism and Cardiovascular Diseases. 31. 10.1016/j.numecd.2020.11.016.Keywords
AnthocyaninsFlavanones
Stevia
Sucralose
Sucrose
Metabolites
UHPLC-ESI-MS/MS
Abstract
The overconsumption of sucrose is closely related to sugar-sweetened beverages and one of the main factors associated with the increase of metabolic diseases, such as type 2 diabetes, obesity, and insulin resistance. So, the addition of alternative sweeteners to new fruit-based drinks could contribute to minimizing the incidence or severity of these pathologies. Nevertheless, current knowledge on the influence of these additives on the bioactive compounds present in these beverages is still scarce.new-onset hypertension, but few data were published in Asian. We aimed to investigate the association of lipid profiles with new-onset hypertension in a Chinese community-based non-hypertensive cohort without lipid-lowering treatment (n = 1802). Hence, to contribute to the understanding of this issue, the plasma concentration of phenolic compounds (anthocyanins and flavanones), after the ingestion of a new maqui-citrus-based beverage, supplemented with sucrose (natural high caloric), stevia ...
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