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dc.contributor.authorVelázquez Blázquez, José Sebastián 
dc.contributor.authorCavas Martínez, Francisco 
dc.contributor.authorBolarín Guillén, José Miguel 
dc.contributor.authorAlió Sanz, Jorge Luciano
dc.identifier.citationVelázquez J.S., Cavas F., Bolarín J.M., Alió J. (2020) Comparison of Corneal Morphologic Parameters and High Order Aberrations in Keratoconus and Normal Eyes. In: Rojas I., Valenzuela O., Rojas F., Herrera L., Ortuño F. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2020. Lecture Notes in Computer Science, vol 12108. Springer, Cham.
dc.description.abstractThe aim of this study is evaluating the influence of corneal geometry in the optical system’s aberrations, and its usefulness as diagnostic criterion for keratoconus.159 normal eyes (normal group, mean age 37.8 ± 11.6 years) and 292 eyes with the diagnosis of keratoconus (keratoconus group, mean age 42.2 ± 17.6 years) were included in this study. All eyes received a comprehensive ophthalmologic examination. A virtual 3D model of each eye was made using CAD software and different anatomical parameters related with surface and volume were measured. Statistically significant differences were found for all anatomical parameters (all p < 0.001). AUROC analysis showed that all parameters reached values above 0.7, with the exception of the total corneal surface area (TCSAA-S). In conclusion, the methodology explained in this research, that bases in anatomical parameters obtained from a virtual corneal model, allow to analyze the diagnostic value of corneal geometry correlation with optical aberrations in keratoconus pathology.es_ES
dc.description.sponsorshipThis publication has been carried out in the framework of the Thematic Network for Co-Operative Research in Health (RETICS), reference number RD16/0008/0012, financed by the Carlos III Health Institute–General Subdirection of Networks and Cooperative Investigation Centers (R&D&I National Plan 2013–2016) and the European Regional Development Fund (FEDER).es_ES
dc.publisherSpringer, Chames_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.titleComparison of corneal morphologic parameters and high order aberrations in keratoconus and normal eyeses_ES
dc.subjectCorneal Apexes_ES
dc.subjectComputer-Aided Design (CAD)es_ES
dc.subjectComputational modellinges_ES
dc.subjectScheimpflug technologyes_ES
dc.subject.otherExpresión Gráfica en Ingenieríaes_ES
dc.subject.unesco3201.09 Oftalmologíaes_ES
dc.subject.unesco1203.09 Diseño Con Ayuda del Ordenadores_ES
dc.contributor.funderInstituto de Salud Carlos IIIes_ES
dc.contributor.funderFondo Europeo de Desarrollo Regional (FEDER)es_ES

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Atribución-NoComercial-SinDerivadas 3.0 España
Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 España