TY - JOUR 
A1 - Alifa Pintado, Ramón
AU - Piñero Llorens, David Pablo
AU - Velázquez Blázquez, José Sebastián
AU - Alió del Barrio, Jorge Luis
AU - Cavas Martínez, Francisco
AU - Alió Sanz, Jorge Luciano
T1 - Changes in the 3D corneal structure and morphogeometric properties in keratoconus after corneal collagen crosslinking
Y1 - 2020
SN - 2075-4418
UR - http://hdl.handle.net/10317/9331
AB - Keratoconus is an ectatic disorder that is presently considered one of the most prevalent reasons for keratoplasty. Corneal collagen crosslinking (CXL) is the only proven treatment option available that is capable of halting the progression of the disease by stabilizing the cone in 90% of cases, and by also reducing refractive error and maximal keratometry. This study assesses, by means of a 3D morphogeometric analysis procedure developed by our research team, the corneal structure changes that occur immediately after CXL treatment and during a 6 month follow-up period. A total of 19 eyes from 19 patients diagnosed with keratoconus who underwent CXL were included, and several variables derived from the morphogeometric analysis were calculated and evaluated for the pre-operative, 3 month postoperative, and 6 month postoperative states. Significant reductions were detected in central corneal thickness and corneal spherical-like root mean square (RMS) 3 months after surgery, with non-significant regression of the e_ect afterward. Significant reductions in the total corneal area/volume were found, with some levels of regression after 6 months in certain volumetric parameters. In conclusion, the eyes with higher values for morphogeometric parameters—posterior apex deviation (PAD), anterior minimum thickness point deviation (AMTPD), and posterior mínimum thickness point deviation (PMTPD)—seemed more likely to undergo aberrometric improvement as a result of CXL surgery.
KW - Expresión Gráfica en Ingeniería
KW - Anterior segment
KW - Tomography
KW - Surgery
KW - Geometry
KW - CXL
KW - 2209 Óptica
LA - eng
PB - MDPI
ER -