Mostrar el registro sencillo del ítem
Alternative sweeteners modify the urinary excretion of flavanones metabolites ingested through a new maqui-berry beverage
dc.contributor.author | Agulló García, Vicente | |
dc.contributor.author | Domínguez Perles, Raúl | |
dc.contributor.author | Moreno Fernández, Diego Ángel | |
dc.contributor.author | Zafrilla Rentero, María Pilar | |
dc.contributor.author | García Viguera, Cristina | |
dc.date.accessioned | 2021-07-15T08:09:54Z | |
dc.date.available | 2021-07-15T08:09:54Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Agulló, V.; Domínguez-Perles, R.; Moreno, D.A.; Zafrilla, P.; García-Viguera, C. Alternative Sweeteners Modify the Urinary Excretion of Flavanones Metabolites Ingested through a New Maqui-Berry Beverage. Foods 2020, 9, 41. https://doi.org/10.3390/foods9010041 | es_ES |
dc.identifier.issn | 2304-8158 | |
dc.description.abstract | Dietary sugar has been largely related to the onset of metabolic diseases such as type 2 diabetes and obesity, among others. The growing awareness on the close relationship between the dietary habits and this health disturbance has encouraged the development of new beverages using alternative sweeteners that could contribute to combat the above referred pathophysiological disorders. To gain further insight into this issue, the present work, upon an acute dietary intervention, evaluated the urinary excretion of flavanones ingested through polyphenols-rich beverages composed of maqui berry and citrus, with the aim of establishing the highest urinary excretion rate and metabolite profiles. The functional beverages evaluated were supplemented with a range of sweeteners including sucrose (natural and high caloric), stevia (natural and non-caloric), and sucralose (artificial and non-caloric) as an approach that would allow reducing the intake of sugars and provide bioactive phenolics (flavanones). The juices developed were ingested by volunteers (n = 20) and the resulting flavanones and their phase II metabolites in urine were analyzed by Ultra-High Performance Liquid Chromatography ElectroSpray Ionization Mass Spectrometry (UHPLC-ESI-MS/MS). A total of 16 metabolites were detected: eriodyctiol, naringenin, and homoeriodyctiol derivatives, where peak concentrations were attained 3.5 h after beverage intake. Sucralose and stevia were the sweeteners that provided the highest urinary excretion for most compounds. Sucrose did not provide a remarkable higher elimination through urine of any compounds in comparison with sucralose or stevia. These results propose two alternative sweeteners to sucrose (sucralose and stevia), an overused, high caloric sweetener that promotes some metabolic disease | es_ES |
dc.description.sponsorship | This work was partially funded by the Spanish MINECO through Research Project AGL2016-75332-C2-1-R. VA was supported by a FPI grant (BES-2017-079754). The authors thank the English expert reviewer (Mario Fon) for the revision of the English style and grammar. | es_ES |
dc.format | application/pdf | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.relation.ispartof | Effect of alternative sweeteners on the bioavailability and bioactivity of anthocyanins and flavanones from a maqui-lemon-based beverage | es_ES |
dc.relation.uri | http://hdl.handle.net/10317/9590 | es_ES |
dc.rights | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.title | Alternative sweeteners modify the urinary excretion of flavanones metabolites ingested through a new maqui-berry beverage | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.subject | Dietary intervention | es_ES |
dc.subject | Maqui-citrus juice | es_ES |
dc.subject | Flavanones | es_ES |
dc.subject | Urinary excretion | es_ES |
dc.subject | UHPLC-ESI-QqQ-MS/MS | es_ES |
dc.identifier.uri | http://hdl.handle.net/10317/9639 | |
dc.identifier.doi | 10.3390/foods9010041 | |
dc.identifier.url | https://www.mdpi.com/2304-8158/9/1/41 | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.relation.projectID | AGL2016-75332-C2-1-R | es_ES |
dc.subject.unesco | 3309 Tecnología de Los Alimentos | es_ES |
dc.contributor.funder | Ministerio de Economía y Empresa | es_ES |
Ficheros en el ítem
Este ítem aparece en la(s) siguiente(s) colección(ones)
-
Artículos [1752]
Redes sociales