Relationship between corneal morphogeometrical properties and biomechanical parameters derived from dynamic bidirectional air applanation measurement procedure in keratoconus
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AuthorCavas Martínez, Francisco; Piñero Llorens, David Pablo; Velázquez Blázquez, José Sebastián; Mira Pérez, Jorge; Alió Sanz, Jorge Luciano
Knowledge AreaExpresión Gráfica en Ingeniería
SponsorsThis publication was carried out in the framework of the Thematic Network for Co-Operative Research in Health (RETICS) reference number RD12/0034/0007 and RD16/0008/0012, financed by the Carlos III Health Institute—General Subdirection of Networks and Cooperative Investigation Centers (R&D&I National Plan 2008–2011) and the European Regional Development Fund (FEDER). The author David P. Piñero has been supported by the Ministry of Economy, Industry, and Competitiveness of Spain within the program Ramón y Cajal, RYC-2016-20471.
Bibliographic CitationCavas F, Piñero D, Velázquez JS, Mira J, Alió JL. Relationship between Corneal Morphogeometrical Properties and Biomechanical Parameters Derived from Dynamic Bidirectional Air Applanation Measurement Procedure in Keratoconus. Diagnostics. 2020; 10(9):640. https://doi.org/10.3390/diagnostics10090640
The morphogeometric analysis of the corneal structure has become a clinically relevant diagnostic procedure in keratoconus (KC) as well as the in vivo evaluation of the corneal biomechanical properties. However, the relationship between these two types of metrics is still not well understood. The current study investigated the relationship of corneal morphogeometry and volume with two biomechanical parameters: corneal hysteresis (CH) and corneal resistance factor (CRF), both provided by an Ocular Response Analyzer (Reichert). It included 109 eyes from 109 patients (aged between 18 and 69 years) with a diagnosis of keratoconus (KC) who underwent a complete eye examination including a comprehensive corneal topographic analysis with the Sirius system (CSO). With the topographic information obtained, a morphogeometric and volumetric analysis was performed, defining di_erent variables of clinical use. CH and CRF were found to be correlated with these variables, but this correlation was highly ...
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