Comparative evaluation of methods for obtaining the stress-free geometry of keratoconus corneas with different levels of severity
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Gómez García, Carmelo; Piñero Llorens, David Pablo; Alió Sanz, Jorge Luciano; Cavas Martínez, FranciscoÁrea de conocimiento
Expresión Gráfica en IngenieríaPatrocinadores
This publication was carried out within the framework of the project “Desarrollo y validación de un nuevo concepto de caracterización biomecánica-morfofuncional de la córnea” reference number DTS21/00103. This project has been funded by Instituto de Salud Carlos III (ISCIII) and co-funded by the European Union.Fecha de publicación
2023-12-28Editorial
ElsevierCita bibliográfica
GÓMEZ GARCÍA, C. et al. Comparative evaluation of methods for obtaining the stress-free geometry of keratoconus corneas with different levels of severity. En: Computers in Biology and Medicine. 2024, 170: 107870. https://doi.org/10.1016/j.compbiomed.2023.107870Revisión por pares
siPalabras clave
Corneal biomechanicsFinite elements
Patient-specific models
Corneal ectasia
Resumen
A biomechanical model that simulates the physiological pressure load on the cornea without considering the stresses in vivo will result in an overstress or underestimation of the stress field and incorrect deformation of the corneal structure. Therefore, it is essential to propose numerical models that consider the stress-free geometry of the cornea. In this study, the Displacement and Pre-stress methods were compared to obtain the stress-free geometry (S-FG) and the physiological estimated geometry (P-EG), based on the patient-specific geometric behavior and the computational time required to reach each geometry. The same shape and contour conditions were considered in the models obtained from both methods for each of the pathological scenarios analyzed. Both methods behaved differently to obtain the free geometry, and this difference increased with the severity grade of the disease. However, they behaved in a similar way to reach the physiological estimated geometry. The Displacement ...
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