Keratoconus detection based on a new corneal volumetric analysis
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AutorCavas Martínez, Francisco; Bataille, Laurent Guy Françoise; García Fernández Pacheco, Daniel; Fernández Cañavate, Francisco José; Alió Sanz, Jorge Luciano
Área de conocimientoExpresión Gráfica en Ingeniería
PatrocinadoresThis publication has been carried out in the framework and with the financial support of the Thematic Network for Co-Operative Research in Health (RETICS) reference number RD16/0008/0012, financed by the Carlos III Health Institute – General Subdirection of Networks and Cooperative Investigation Centers (R&D&I National Plan 2008–2011) and the European Regional Development Fund (FEDER).
Fecha de publicación2017-11-20
EditorialNature Publishing Group
Cita bibliográficaCAVAS MARTÍNEZ, Francisco et al. Keratoconus detection based on a new corneal volumetric analysis. En: Scientific reports, vol. 7, n.1, 2017. ISSN: 2045-2322
Palabras clavePachymetric parameters
There are numerous tomographic indices for the detection of keratoconus risk. When the indexes based on corneal volume are analyzed, two problems are presented: on the one hand, they are not very sensitive to the detection of incipient cases of keratoconus because they are not locally defined in the primary developmental region of the structural abnormalities; and on the other hand, they do not register the geometric decompensation driven by the asymmetry present during the disease progression. This work performed a morphogeometric modeling of the cornea by the aid of CAD tools and using raw topographic data (Sirius system, CSO, Firenze). For this method, four singular points present on the corneal surfaces were located and the following parameters based on corneal volume were calculated: VOLmct, defined by the points of minimal thickness; VOLaap, defined by the anterior corneal apex, and VOLpap, defined by the posterior corneal apex. The results demonstrate that a further reduction of ...
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